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Tottenham Hotspur 3 - 2 Southampton
Osasuna 1 - 2 Sevilla
West Ham United 0 - 2 Manchester United
Cardiff City 3 - 6 Liverpool
Chelsea 6 - 0 Arsenal
Celta Vigo 0 - 2 Malaga
Lorient 0 - 1 Paris Saint-Germain
SC Freiburg 3 - 1 Werder Bremen
FC Salzburg 1 - 2 FC Basel
Napoli 2 - 2 FC Porto
Real Betis 0 - 2 Sevilla [PEN: 3-4]
Valencia 1 - 0 PFC Ludogorets Razgrad